Mistress Death

Part 1: The Dossier: An At-a-Glance Summary

1)
Mistress Death is philosophically distinct from the many “death gods” of Earth's pantheons, such as the Asgardian Hela, the Olympian Pluto, or the demon-lord Mephisto. While these beings have dominion over their respective afterlives and command death-related powers, they are racially defined beings who rule specific realms. Mistress Death is the universal, abstract concept of death itself, to which even gods are ultimately subject.
2)
Jim Starlin has stated that his initial inspiration for the physical appearance of Thanos, and by extension his obsession, came from the Greek concepts of Eros (love/life) and Thanatos (death). Thanos's brother is named Eros (Starfox), making the Mad Titan the literal embodiment of the “death drive.”
3)
In the crossover series JLA/Avengers, Death's realm is one of the few places shown to exist independently in both the Marvel and DC universes, reinforcing her status as a fundamental constant of reality itself.
4)
One of the rare instances of Death speaking at length is in the 1992 series The Incredible Hulk #391. During a near-death experience, the Hulk is transported to her realm, where she engages in a philosophical debate with him about his purpose and the nature of his rage.
5)
The question of “Can Mistress Death die?” was explored in the storyline The Thanos Imperative. In the “Cancerverse” (Earth-10011), the heroes of that reality made a pact with the Many-Angled Ones to destroy their version of Death. The result was a universe of cancerous, immortal life that could not be stopped, demonstrating that her existence is a cosmic necessity.
6)
Key Reading List: Captain Marvel #26-33 (First Appearance and Thanos Saga), The Infinity Gauntlet #1-6 (Definitive Story), Deadpool vs. Thanos #1-4 (Explores Deadpool relationship), Thanos (2016) #13-18 (“Thanos Wins” arc).